Proteins/UNIPROT:Q8NDX1

PSD4

ProteinUNIPROT:Q8NDX1

Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate..

Function from UniProtKB (Q8NDX1), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

8 statements

8 statements · 3 reference databases · Subject: PSD4 · Sources: gene ontology, Hetionet, WikiPathways

Order

MAB21L4 covaries with PSD4ProteinHetionet hetionet:covaries:23550-79919Inferred only
ARF6 interacts with PSD4ProteinHetionet hetionet:interacts:23550-382Inferred only
PSD4 interacts with ARL14ProteinHetionet hetionet:interacts:23550-80117Inferred only
USP9X interacts with PSD4ProteinHetionet hetionet:interacts:23550-8239Inferred only
PSD4 participates in 2q13 copy number variation syndromePathwayWikiPathways WP5222Inferred only
PSD4 regulates regulation of ARF protein signal transductionBiological processgene ontology Q8NDX1|GO:0032012Inferred only
GNA11 increases the expression of PSD4ProteinHetionet hetionet:regulates:2767-23550Inferred only
OVOL2 increases the expression of PSD4ProteinHetionet hetionet:regulates:58495-23550Inferred only

Other names

6 names

Resolves to: PSD4

Also called: EFA6BExchange factor for ADP-ribosylation factor guanine nucleotide factor 6 BExchange factor for ARF6 BPleckstrin homology and SEC7 domain-containing protein 4Telomeric of interleukin-1 cluster proteinTIC

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