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Proteins/UNIPROT:P22891

PROZ

Protein·UNIPROT:P22891

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Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles. Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids.

Function from UniProtKB (P22891), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

13 statements

13 statements · 3 reference databases · Subject: PROZ · Sources: Hetionet, Reactome, WikiPathways

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MCF2L covaries with PROZProteinHetionet hetionet:covaries:23263-8858Inferred only
XKR5 covaries with PROZProteinHetionet hetionet:covaries:389610-8858Inferred only
PROZ participates in Coagulation pathwayPathwayReactome R-HSA-9769740Inferred only
PROZ participates in Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activationPathwayReactome R-HSA-163841Inferred only
PROZ participates in Gamma-carboxylation of protein precursorsPathwayReactome R-HSA-159740Inferred only
PROZ participates in Gamma-carboxylation, transport, and amino-terminal cleavage of proteinsPathwayReactome R-HSA-159854Inferred only
PROZ participates in HemostasisPathwayReactome R-HSA-109582Inferred only
PROZ participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
PROZ participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only
PROZ participates in Regulation of clotting cascadePathwayReactome R-HSA-9769739Inferred only
PROZ participates in Removal of aminoterminal propeptides from gamma-carboxylated proteinsPathwayReactome R-HSA-159782Inferred only
PROZ participates in Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatusPathwayReactome R-HSA-159763Inferred only

Show the remaining 1

PROZ participates in Vitamin K metabolism and activation of dependent proteinsPathwayWikiPathways WP5186Inferred only

Other names

1 name

Resolves to: PROZ

Also called: Vitamin K-dependent protein Z

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