Proteins/UNIPROT:Q15063

POSTN

ProteinUNIPROT:Q15063

Induces cell attachment and spreading and plays a role in cell adhesion. Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX (By similarity)..

Function from UniProtKB (Q15063), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

9 statements

9 statements · 3 reference databases · Subject: POSTN · Sources: gene ontology, Hetionet, WikiPathways

Order

POSTN interacts with TRAPPC2LProteinHetionet hetionet:interacts:10631-51693Inferred only
POSTN participates in Amplification and expansion of oncogenic pathways as metastatic traitsPathwayWikiPathways WP3678Inferred only
POSTN participates in Hypothesized pathways in pathogenesis of cardiovascular diseasePathwayWikiPathways WP3668Inferred only
POSTN participates in TGFB Smad signalingPathwayWikiPathways WP5382Inferred only
POSTN regulates negative regulation of cell-matrix adhesionBiological processgene ontology Q15063|GO:0001953Inferred only
POSTN regulates negative regulation of substrate adhesion-dependent cell spreadingBiological processgene ontology Q15063|GO:1900025Inferred only
POSTN regulates positive regulation of chemokine (C-X-C motif) ligand 2 productionBiological processgene ontology Q15063|GO:2000343Inferred only
POSTN regulates positive regulation of smooth muscle cell migrationBiological processgene ontology Q15063|GO:0014911Inferred only
POSTN regulates regulation of systemic arterial blood pressureBiological processgene ontology Q15063|GO:0003073Inferred only

Other names

4 names

Resolves to: POSTN

Also called: OSF-2OSF2Osteoblast-specific factor 2PN

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