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Proteins/UNIPROT:Q96PX9
Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. Plays a role in actin cytoskeletal remodeling in the late stage of cell-cell junction formation by regulating the contractility of actin filaments, which prompts the conversion from 'open' to 'closed' junctions..
Function from UniProtKB (Q96PX9), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
7 statements
7 statements · 3 reference databases · Subject: PLEKHG4B · Sources: gene ontology, Hetionet, Reactome
3 names
Resolves to: PLEKHG4B