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Proteins/UNIPROT:Q9H7P9
May be a transforming oncogene with exchange activity for CDC42 (By similarity). May be a guanine-nucleotide exchange factor (GEF) for RAC1 and CDC42. Activated by the binding to subunits beta and gamma of the heterotrimeric guanine nucleotide-binding protein (G protein). Involved in the regulation of actin polymerization..
Function from UniProtKB (Q9H7P9), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
22 statements
22 statements · 3 reference databases · Subject: PLEKHG2 · Sources: gene ontology, Hetionet, Reactome
2 names
Resolves to: PLEKHG2