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Proteins/UNIPROT:Q15111
Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity). Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as an inhibitor of PPP1C..
Function from UniProtKB (Q15111), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
5 statements
5 statements · 3 reference databases · Subject: PLCL1 · Sources: gene ontology, Hetionet, WikiPathways
4 names
Resolves to: PLCL1