Proteins/UNIPROT:Q9NV79

PCMTD2

ProteinUNIPROT:Q9NV79

May act as a substrate recognition component of an ECS (Elongin BC-CUL5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May bind to the methyltransferase cofactor S-adenosylmethionine (AdoMet) via the N-terminal AdoMet binding motif, but probably does not display methyltransferase activity..

Function from UniProtKB (Q9NV79), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

12 statements

12 statements · 1 reference database · Subject: PCMTD2 · Sources: Hetionet

Order

ATP13A2 interacts with PCMTD2ProteinHetionet hetionet:interacts:23400-55251Inferred only
CDC25A increases the expression of PCMTD2ProteinHetionet hetionet:regulates:993-55251Inferred only
CSK decreases the expression of PCMTD2ProteinHetionet hetionet:regulates:1445-55251Inferred only
DDR1 increases the expression of PCMTD2ProteinHetionet hetionet:regulates:780-55251Inferred only
ESPL1 increases the expression of PCMTD2ProteinHetionet hetionet:regulates:9700-55251Inferred only
MTOR increases the expression of PCMTD2ProteinHetionet hetionet:regulates:2475-55251Inferred only
NAB1 increases the expression of PCMTD2ProteinHetionet hetionet:regulates:4664-55251Inferred only
RAF1 increases the expression of PCMTD2ProteinHetionet hetionet:regulates:5894-55251Inferred only
RORC increases the expression of PCMTD2ProteinHetionet hetionet:regulates:6097-55251Inferred only
SRC increases the expression of PCMTD2ProteinHetionet hetionet:regulates:6714-55251Inferred only
TLR9 increases the expression of PCMTD2ProteinHetionet hetionet:regulates:54106-55251Inferred only
TNFAIP3 increases the expression of PCMTD2ProteinHetionet hetionet:regulates:7128-55251Inferred only

Other names

2 names

Resolves to: PCMTD2

Also called: C20orf36Protein-L-isoaspartate O-methyltransferase domain-containing protein 2

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