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Proteins/UNIPROT:Q96MG8
Substrate recognition component of an ECS (Elongin BC-CUL5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Specifically binds to the methyltransferase cofactor S-adenosylmethionine (AdoMet) via the N-terminal AdoMet binding motif, but does not display methyltransferase activity. May provide an alternate maintenance pathway for modified proteins by acting as a damage-specific E3 ubiquitin ligase adaptor protein..
Function from UniProtKB (Q96MG8), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
4 statements
4 statements · 1 reference database · Subject: PCMTD1 · Sources: Hetionet
1 name
Resolves to: PCMTD1