Proteins/UNIPROT:Q9NPG4

PCDH12

ProteinUNIPROT:Q9NPG4

Cellular adhesion molecule that may play an important role in cell-cell interactions at interendothelial junctions (By similarity). Acts as a regulator of cell migration, probably via increasing cell-cell adhesion. Promotes homotypic calcium-dependent aggregation and adhesion and clusters at intercellular junctions (By similarity). Unable to bind to catenins, weakly associates with the cytoskeleton (By similarity)..

Function from UniProtKB (Q9NPG4), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

2 rows

diencephalic-mesencephalic junction dysplasia has a germline basis in PCDH12DiseaseGenCC HGNC:8657|MONDO:0017868Inferred only
diencephalic-mesencephalic junction dysplasia syndrome 1 has a germline basis in PCDH12DiseaseGenCC HGNC:8657|MONDO:0009625Inferred only

Statements

5 statements

5 statements · 1 reference database · Subject: PCDH12 · Sources: Hetionet

Order

C1QTNF5 covaries with PCDH12ProteinHetionet hetionet:covaries:114902-51294Inferred only
GEMIN5 covaries with PCDH12ProteinHetionet hetionet:covaries:25929-51294Inferred only
PCDH12 covaries with MEOX1ProteinHetionet hetionet:covaries:4222-51294Inferred only
PCDH12 covaries with PCDHB10ProteinHetionet hetionet:covaries:51294-56126Inferred only
MYBPC2 interacts with PCDH12ProteinHetionet hetionet:interacts:4606-51294Inferred only

Other names

5 names

Resolves to: PCDH12

Also called: [Cleaved into: Protocadherin-12, secreted form]Vascular cadherin-2Vascular endothelial cadherin-2VE-cad-2VE-cadherin-2

← Every protein Find it in the graph →