Proteins/UNIPROT:Q9BYG5

PARD6B

ProteinUNIPROT:Q9BYG5

Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.

Function from UniProtKB (Q9BYG5), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

32 statements

32 statements · 4 reference databases · Subject: PARD6B · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

NXF3 covaries with PARD6BProteinHetionet hetionet:covaries:56000-84612Inferred only
PARD6B covaries with SLIT1ProteinHetionet hetionet:covaries:6585-84612Inferred only
VILL covaries with PARD6BProteinHetionet hetionet:covaries:50853-84612Inferred only
APP interacts with PARD6BProteinHetionet hetionet:interacts:351-84612Inferred only
CDC42 interacts with PARD6BProteinHetionet hetionet:interacts:84612-998Inferred only
PARD3 interacts with PARD6BProteinHetionet hetionet:interacts:56288-84612Inferred only
PARD6B interacts with PARD3BProteinHetionet hetionet:interacts:117583-84612Inferred only
PARD6A interacts with PARD6BProteinHetionet hetionet:interacts:50855-84612Inferred only
PNMA1 interacts with PARD6BProteinHetionet hetionet:interacts:84612-9240Inferred only
PRKCG interacts with PARD6BProteinHetionet hetionet:interacts:5582-84612Inferred only
PRKCI interacts with PARD6BProteinHetionet hetionet:interacts:5584-84612Inferred only
PRKCZ interacts with PARD6BProteinHetionet hetionet:interacts:5590-84612Inferred only

Show the remaining 20

RAC1 interacts with PARD6BProteinHetionet hetionet:interacts:5879-84612Inferred only
RHOQ interacts with PARD6BProteinHetionet hetionet:interacts:23433-84612Inferred only
UBC interacts with PARD6BProteinHetionet hetionet:interacts:7316-84612Inferred only
YWHAB interacts with PARD6BProteinHetionet hetionet:interacts:7529-84612Inferred only
YWHAH interacts with PARD6BProteinHetionet hetionet:interacts:7533-84612Inferred only
PARD6B participates in 1p36 copy number variation syndromePathwayWikiPathways WP5345Inferred only
PARD6B participates in BDNF signaling in neurodevelopmentPathwayWikiPathways WP5541Inferred only
PARD6B participates in Cell junction organizationPathwayReactome R-HSA-446728Inferred only
PARD6B participates in Cell-Cell communicationPathwayReactome R-HSA-1500931Inferred only
PARD6B participates in Cell-cell junction organizationPathwayReactome R-HSA-421270Inferred only
PARD6B participates in Complement system in neuronal development and plasticityPathwayWikiPathways WP5090Inferred only
PARD6B participates in RHO GTPase cyclePathwayReactome R-HSA-9012999Inferred only
PARD6B participates in RHOV GTPase cyclePathwayReactome R-HSA-9013424Inferred only
PARD6B participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
PARD6B participates in Signaling by Rho GTPasesPathwayReactome R-HSA-194315Inferred only
PARD6B participates in Signaling by Rho GTPases, Miro GTPases and RHOBTB3PathwayReactome R-HSA-9716542Inferred only
PARD6B participates in Smith Magenis and Potocki Lupski syndrome copy number variationPathwayWikiPathways WP5381Inferred only
PARD6B participates in Tight junction interactionsPathwayReactome R-HSA-420029Inferred only
PARD6B regulates regulation of cell migrationBiological processgene ontology Q9BYG5|GO:0030334Inferred only
PARD6B regulates regulation of cellular localizationBiological processgene ontology Q9BYG5|GO:0060341Inferred only

Other names

3 names

Resolves to: PARD6B

Also called: PAR-6 betaPAR-6BPAR6B

← Every protein Find it in the graph →