Proteins/UNIPROT:Q9Y5A7

NUB1

ProteinUNIPROT:Q9Y5A7

Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2..

Function from UniProtKB (Q9Y5A7), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

14 statements

14 statements · 2 reference databases · Subject: NUB1 · Sources: gene ontology, Hetionet

Order

AIPL1 interacts with NUB1ProteinHetionet hetionet:interacts:23746-51667Inferred only
COPB1 interacts with NUB1ProteinHetionet hetionet:interacts:1315-51667Inferred only
FANCA interacts with NUB1ProteinHetionet hetionet:interacts:2175-51667Inferred only
FAT1 interacts with NUB1ProteinHetionet hetionet:interacts:2195-51667Inferred only
NEDD8 interacts with NUB1ProteinHetionet hetionet:interacts:4738-51667Inferred only
PSMD2 interacts with NUB1ProteinHetionet hetionet:interacts:51667-5708Inferred only
PSMD4 interacts with NUB1ProteinHetionet hetionet:interacts:51667-5710Inferred only
SNCAIP interacts with NUB1ProteinHetionet hetionet:interacts:51667-9627Inferred only
TP53 interacts with NUB1ProteinHetionet hetionet:interacts:51667-7157Inferred only
UBC interacts with NUB1ProteinHetionet hetionet:interacts:51667-7316Inferred only
UBD interacts with NUB1ProteinHetionet hetionet:interacts:10537-51667Inferred only
UBE2K interacts with NUB1ProteinHetionet hetionet:interacts:3093-51667Inferred only

Show the remaining 2

NUB1 regulates positive regulation of proteasomal ubiquitin-dependent protein catabolic processBiological processgene ontology Q9Y5A7|GO:0032436Inferred only
NUB1 regulates regulation of ubiquitin-dependent protein catabolic processBiological processgene ontology Q9Y5A7|GO:2000058Inferred only

Other names

3 names

Resolves to: NUB1

Also called: Negative regulator of ubiquitin-like proteins 1NYREN18Renal carcinoma antigen NY-REN-18

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