Proteins/UNIPROT:Q6X4W1

NSMF

ProteinUNIPROT:Q6X4W1

Couples NMDA-sensitive glutamate receptor signaling to the nucleus and triggers long-lasting changes in the cytoarchitecture of dendrites and spine synapse processes. Part of the cAMP response element-binding protein (CREB) shut-off signaling pathway. Stimulates outgrowth of olfactory axons and migration of gonadotropin-releasing hormone (GnRH) and luteinizing-hormone-releasing hormone (LHRH) neuronal cells..

Function from UniProtKB (Q6X4W1), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

2 rows

hypogonadotropic hypogonadism has a germline basis in NSMFDiseaseGenCC HGNC:29843|MONDO:0018555Inferred only
hypogonadotropic hypogonadism 9 with or without anosmia has a germline basis in NSMFDiseaseGenCC HGNC:29843|MONDO:0013911Inferred only

Statements

31 statements

31 statements · 3 reference databases · Subject: NSMF · Sources: gene ontology, Hetionet, WikiPathways

Order

ABCA2 covaries with NSMFProteinHetionet hetionet:covaries:20-26012Inferred only
NSMF covaries with ACAP3ProteinHetionet hetionet:covaries:116983-26012Inferred only
ASPDH covaries with NSMFProteinHetionet hetionet:covaries:26012-554235Inferred only
NSMF covaries with BAHCC1ProteinHetionet hetionet:covaries:26012-57597Inferred only
CDH20 covaries with NSMFProteinHetionet hetionet:covaries:26012-28316Inferred only
EIF2S3 covaries with NSMFProteinHetionet hetionet:covaries:1968-26012Inferred only
NSMF covaries with FBRSL1ProteinHetionet hetionet:covaries:26012-57666Inferred only
NSMF covaries with GPR85ProteinHetionet hetionet:covaries:26012-54329Inferred only
KCTD12 covaries with NSMFProteinHetionet hetionet:covaries:115207-26012Inferred only
NSMF covaries with LHFPL3ProteinHetionet hetionet:covaries:26012-375612Inferred only
NSMF covaries with NHLRC4ProteinHetionet hetionet:covaries:26012-283948Inferred only
NSMF covaries with PANX2ProteinHetionet hetionet:covaries:26012-56666Inferred only

Show the remaining 19

NSMF covaries with POLD1ProteinHetionet hetionet:covaries:26012-5424Inferred only
NSMF covaries with RHBDL1ProteinHetionet hetionet:covaries:26012-9028Inferred only
SCN1A covaries with NSMFProteinHetionet hetionet:covaries:26012-6323Inferred only
TNNI1 covaries with NSMFProteinHetionet hetionet:covaries:26012-7135Inferred only
NSMF covaries with YTHDC2ProteinHetionet hetionet:covaries:26012-64848Inferred only
NSMF covaries with ZNF423ProteinHetionet hetionet:covaries:23090-26012Inferred only
GFI1B interacts with NSMFProteinHetionet hetionet:interacts:26012-8328Inferred only
HSPB3 interacts with NSMFProteinHetionet hetionet:interacts:26012-8988Inferred only
RAN interacts with NSMFProteinHetionet hetionet:interacts:26012-5901Inferred only
NSMF participates in Neuroinflammation and glutamatergic signalingPathwayWikiPathways WP5083Inferred only
NSMF regulates positive regulation of neuron migrationBiological processgene ontology Q6X4W1|GO:2001224Inferred only
NSMF regulates regulation of dendrite morphogenesisBiological processgene ontology Q6X4W1|GO:0048814Inferred only
NSMF regulates regulation of neuron apoptotic processBiological processgene ontology Q6X4W1|GO:0043523Inferred only
NSMF regulates regulation of neuronal synaptic plasticityBiological processgene ontology Q6X4W1|GO:0048168Inferred only
CHD8 increases the expression of NSMFProteinHetionet hetionet:regulates:57680-26012Inferred only
ISG20 decreases the expression of NSMFProteinHetionet hetionet:regulates:3669-26012Inferred only
MECP2 decreases the expression of NSMFProteinHetionet hetionet:regulates:4204-26012Inferred only
MRPS2 decreases the expression of NSMFProteinHetionet hetionet:regulates:51116-26012Inferred only
PSRC1 decreases the expression of NSMFProteinHetionet hetionet:regulates:84722-26012Inferred only

Other names

3 names

Resolves to: NSMF

Also called: Nasal embryonic LHRH factorNasal embryonic luteinizing hormone-releasing hormone factorNELF

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