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Proteins/UNIPROT:P50391

NPY4R

Protein·UNIPROT:P50391

Open in the graph

G protein-coupled receptor for PPY/pancreatic polypeptide/PP, NPY/neuropeptide Y and PYY/peptide YY that is negatively coupled to cAMP. The rank order of affinity for these polypeptides and their derivatives is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13-36) > PP (31-36) > NPY free acid..

Function from UniProtKB (P50391), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

13 statements

13 statements · 3 reference databases · Subject: NPY4R · Sources: Hetionet, Reactome, WikiPathways

Search this listOrder

AKNA covaries with NPY4RProteinHetionet hetionet:covaries:5540-80709Inferred only
COL27A1 covaries with NPY4RProteinHetionet hetionet:covaries:5540-85301Inferred only
GRAMD1A covaries with NPY4RProteinHetionet hetionet:covaries:5540-57655Inferred only
PPY interacts with NPY4RProteinHetionet hetionet:interacts:5539-5540Inferred only
NPY4R participates in Class A/1 (Rhodopsin-like receptors)PathwayReactome R-HSA-373076Inferred only
NPY4R participates in G alpha (i) signalling eventsPathwayReactome R-HSA-418594Inferred only
NPY4R participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
NPY4R participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only
NPY4R participates in GPCRs class A rhodopsin likePathwayWikiPathways WP455Inferred only
NPY4R participates in Peptide GPCRsPathwayWikiPathways WP24Inferred only
NPY4R participates in Peptide ligand-binding receptorsPathwayReactome R-HSA-375276Inferred only
NPY4R participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only

Show the remaining 1

NPY4R participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only

Other names

4 names

Resolves to: NPY4R

Also called: NPY4-RPancreatic polypeptide receptor 1PP1PPYR1

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