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Proteins/UNIPROT:Q7Z494
Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements..
Function from UniProtKB (Q7Z494), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
8 rows
18 statements
18 statements · 4 reference databases · Subject: NPHP3 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
2 names
Resolves to: NPHP3