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Proteins/UNIPROT:Q9NZG7
Its role in unclear. In contrast to NINJ1 paralog, does not mediate plasma membrane rupture (cytolysis) downstream of necroptotic and pyroptotic programmed cell death. While it is able to oligomerize and form filaments, filaments are curved toward the intracellular space, preventing circularization to mediate plasma membrane rupture. May act as a homophilic transmembrane adhesion molecule involved in nerve regeneration. Promotes axonal growth..
Function from UniProtKB (Q9NZG7), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
4 statements
4 statements · 1 reference database · Subject: NINJ2 · Sources: Hetionet
2 names
Resolves to: NINJ2