Proteins/UNIPROT:Q9BR09

NEURL2

ProteinUNIPROT:Q9BR09

Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma (By similarity)..

Function from UniProtKB (Q9BR09), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

5 statements

5 statements · 2 reference databases · Subject: NEURL2 · Sources: Hetionet, Reactome

Order

NEURL2 covaries with IGFLR1ProteinHetionet hetionet:covaries:140825-79713Inferred only
CTNNB1 interacts with NEURL2ProteinHetionet hetionet:interacts:140825-1499Inferred only
NEURL2 participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
NEURL2 participates in NeddylationPathwayReactome R-HSA-8951664Inferred only
NEURL2 participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only

Other names

2 names

Resolves to: NEURL2

Also called: C20orf163Neuralized-like protein 2

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