Proteins/UNIPROT:Q5TEU4

NDUFAF5

ProteinUNIPROT:Q5TEU4

Arginine hydroxylase that mediates hydroxylation of 'Arg-111' of NDUFS7 and is involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I, MT-ND1) at early stages. May also have methyltransferase activity (Probable)..

Function from UniProtKB (Q5TEU4), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

5 rows

Leigh syndrome has a germline basis in NDUFAF5DiseaseGenCC HGNC:15899|MONDO:0009723Inferred only
mitochondrial complex I deficiency has a germline basis in NDUFAF5DiseaseGenCC HGNC:15899|MONDO:0100133Inferred only
mitochondrial complex I deficiency, nuclear type 16 has a germline basis in NDUFAF5DiseaseGenCC HGNC:15899|MONDO:0032621Inferred only
mitochondrial complex I deficiency, nuclear type 3 has a germline basis in NDUFAF5DiseaseGenCC HGNC:15899|MONDO:0032608Inferred only
mitochondrial disease has a germline basis in NDUFAF5DiseaseGenCC HGNC:15899|MONDO:0044970Inferred only

Statements

6 statements

6 statements · 2 reference databases · Subject: NDUFAF5 · Sources: Hetionet, Reactome

Order

MLNR covaries with NDUFAF5ProteinHetionet hetionet:covaries:2862-79133Inferred only
UBC interacts with NDUFAF5ProteinHetionet hetionet:interacts:7316-79133Inferred only
NDUFAF5 participates in Aerobic respiration and respiratory electron transportPathwayReactome R-HSA-1428517Inferred only
NDUFAF5 participates in Complex I biogenesisPathwayReactome R-HSA-6799198Inferred only
NDUFAF5 participates in MetabolismPathwayReactome R-HSA-1430728Inferred only
NDUFAF5 participates in Respiratory electron transportPathwayReactome R-HSA-611105Inferred only

Other names

3 names

Resolves to: NDUFAF5

Also called: C20orf7NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5Putative methyltransferase NDUFAF5

← Every protein Find it in the graph →