Proteins/UNIPROT:B1AL88

NALF1

ProteinUNIPROT:B1AL88

Auxilary subunit component of the NALCN channelosome complex, which regulates the resting membrane potential by depolarizing sodium leak currents. The NALCN channelosome complex is a voltage-gated ion channel responsible for the resting Na(+) permeability that controls neuronal excitability. The NALCN channelosome is constitutively active and conducts monovalent cations but is blocked by physiological concentrations of extracellular divalent cations..

Function from UniProtKB (B1AL88), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

5 statements

5 statements · 2 reference databases · Subject: NALF1 · Sources: gene ontology, Hetionet

Order

ANKRD34C covaries with NALF1ProteinHetionet hetionet:covaries:390616-728215Inferred only
SAMD15 covaries with NALF1ProteinHetionet hetionet:covaries:161394-728215Inferred only
SCRT2 covaries with NALF1ProteinHetionet hetionet:covaries:728215-85508Inferred only
VSTM1 covaries with NALF1ProteinHetionet hetionet:covaries:284415-728215Inferred only
NALF1 regulates regulation of neuronal action potentialBiological processgene ontology B1AL88|GO:0098908Inferred only

Other names

4 names

Resolves to: NALF1

Also called: FAM155ANALCN channel auxiliary factor 1NLF-1Transmembrane protein FAM155A

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