Proteins/UNIPROT:Q8NFW9

MYRIP

ProteinUNIPROT:Q8NFW9

Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase A-anchoring protein (AKAP). May act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release (By similarity)..

Function from UniProtKB (Q8NFW9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

20 statements

20 statements · 4 reference databases · Subject: MYRIP · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

MYRIP covaries with HEXIM2ProteinHetionet hetionet:covaries:124790-25924Inferred only
OR52E8 covaries with MYRIPProteinHetionet hetionet:covaries:25924-390079Inferred only
SMIM48 covaries with MYRIPProteinHetionet hetionet:covaries:25924-728392Inferred only
MYRIP covaries with WASHC2CProteinHetionet hetionet:covaries:253725-25924Inferred only
CAV1 interacts with MYRIPProteinHetionet hetionet:interacts:25924-857Inferred only
CREB1 interacts with MYRIPProteinHetionet hetionet:interacts:1385-25924Inferred only
GRB2 interacts with MYRIPProteinHetionet hetionet:interacts:25924-2885Inferred only
MYO7A interacts with MYRIPProteinHetionet hetionet:interacts:25924-4647Inferred only
NCK1 interacts with MYRIPProteinHetionet hetionet:interacts:25924-4690Inferred only
PIK3R1 interacts with MYRIPProteinHetionet hetionet:interacts:25924-5295Inferred only
RAB27A interacts with MYRIPProteinHetionet hetionet:interacts:25924-5873Inferred only
MYRIP participates in Deregulation of Rab and Rab effector genes in bladder cancerPathwayWikiPathways WP2291Inferred only

Show the remaining 8

MYRIP participates in Developmental BiologyPathwayReactome R-HSA-1266738Inferred only
MYRIP participates in Insulin processingPathwayReactome R-HSA-264876Inferred only
MYRIP participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
MYRIP participates in MITF-M-dependent gene expressionPathwayReactome R-HSA-9856651Inferred only
MYRIP participates in MITF-M-regulated melanocyte developmentPathwayReactome R-HSA-9730414Inferred only
MYRIP participates in Peptide hormone metabolismPathwayReactome R-HSA-2980736Inferred only
MYRIP participates in Regulation of MITF-M-dependent genes involved in pigmentationPathwayReactome R-HSA-9824585Inferred only
MYRIP regulates positive regulation of insulin secretionBiological processgene ontology Q8NFW9|GO:0032024Inferred only

Other names

6 names

Resolves to: MYRIP

Also called: Exophilin-8Myosin-VIIa- and Rab-interacting proteinSlaC2-cSLAC2CSlp homolog lacking C2 domains cSynaptotagmin-like protein lacking C2 domains C

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