Proteins/UNIPROT:P13349

MYF5

ProteinUNIPROT:P13349

Transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein..

Function from UniProtKB (P13349), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

ophthalmoplegia, external, with rib and vertebral anomalies has a germline basis in MYF5DiseaseGenCC HGNC:7565|MONDO:0032565Inferred only

Statements

24 statements

24 statements · 4 reference databases · Subject: MYF5 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

CEP295 covaries with MYF5ProteinHetionet hetionet:covaries:4617-85459Inferred only
MYF5 covaries with SYTL2ProteinHetionet hetionet:covaries:4617-54843Inferred only
CALM1 interacts with MYF5ProteinHetionet hetionet:interacts:4617-808Inferred only
CALM1 interacts with MYF5ProteinHetionet hetionet:interacts:4617-801Inferred only
CALM1 interacts with MYF5ProteinHetionet hetionet:interacts:4617-805Inferred only
CSNK2A1 interacts with MYF5ProteinHetionet hetionet:interacts:1457-4617Inferred only
CSNK2A2 interacts with MYF5ProteinHetionet hetionet:interacts:1459-4617Inferred only
MYF5 interacts with ELSPBP1ProteinHetionet hetionet:interacts:4617-64100Inferred only
ID1 interacts with MYF5ProteinHetionet hetionet:interacts:3397-4617Inferred only
ID2 interacts with MYF5ProteinHetionet hetionet:interacts:3398-4617Inferred only
ID3 interacts with MYF5ProteinHetionet hetionet:interacts:3399-4617Inferred only
MDFI interacts with MYF5ProteinHetionet hetionet:interacts:4188-4617Inferred only

Show the remaining 12

MYF5 interacts with TCF3ProteinHetionet hetionet:interacts:4617-6929Inferred only
MYF5 participates in Developmental BiologyPathwayReactome R-HSA-1266738Inferred only
MYF5 participates in MyogenesisPathwayReactome R-HSA-525793Inferred only
MYF5 participates in Netrin UNC5B signalingPathwayWikiPathways WP4747Inferred only
MYF5 participates in Pathophysiological roles of DUX4 in FSHD1PathwayWikiPathways WP5342Inferred only
MYF5 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
MYF5 participates in Signaling by TGFB family membersPathwayReactome R-HSA-9006936Inferred only
MYF5 participates in Signaling by TGFBR3PathwayReactome R-HSA-9839373Inferred only
MYF5 participates in TGFBR3 expressionPathwayReactome R-HSA-9839394Inferred only
MYF5 regulates positive regulation of myoblast differentiationBiological processgene ontology P13349|GO:0045663Inferred only
MYF5 regulates positive regulation of skeletal muscle fiber developmentBiological processgene ontology P13349|GO:0048743Inferred only
MYF5 regulates regulation of transcription by RNA polymerase IIBiological processgene ontology P13349|GO:0006357Inferred only

Other names

3 names

Resolves to: MYF5

Also called: BHLHC2Class C basic helix-loop-helix protein 2Myf-5

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