Proteins/UNIPROT:O43347

MSI1

ProteinUNIPROT:O43347

RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity)..

Function from UniProtKB (O43347), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

12 statements

12 statements · 3 reference databases · Subject: MSI1 · Sources: gene ontology, Hetionet, Reactome

Order

OR10P1 covaries with MSI1ProteinHetionet hetionet:covaries:121130-4440Inferred only
PPP6C covaries with MSI1ProteinHetionet hetionet:covaries:4440-5537Inferred only
MSI1 covaries with PRXL2BProteinHetionet hetionet:covaries:127281-4440Inferred only
APP interacts with MSI1ProteinHetionet hetionet:interacts:351-4440Inferred only
MSI1 interacts with PNMA1ProteinHetionet hetionet:interacts:4440-9240Inferred only
MSI1 interacts with UBCProteinHetionet hetionet:interacts:4440-7316Inferred only
MSI1 participates in Axon guidancePathwayReactome R-HSA-422475Inferred only
MSI1 participates in Developmental BiologyPathwayReactome R-HSA-1266738Inferred only
MSI1 participates in Nervous system developmentPathwayReactome R-HSA-9675108Inferred only
MSI1 participates in Regulation of expression of SLITs and ROBOsPathwayReactome R-HSA-9010553Inferred only
MSI1 participates in Signaling by ROBO receptorsPathwayReactome R-HSA-376176Inferred only
MSI1 regulates regulation of translationBiological processgene ontology O43347|GO:0006417Inferred only

Other names

2 names

Resolves to: MSI1

Also called: Musashi-1RNA-binding protein Musashi homolog 1

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