Proteins/UNIPROT:Q96C03

MIEF2

ProteinUNIPROT:Q96C03

Mitochondrial outer membrane protein involved in the regulation of mitochondrial organization. It is required for mitochondrial fission and promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity..

Function from UniProtKB (Q96C03), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

12 statements

12 statements · 3 reference databases · Subject: MIEF2 · Sources: gene ontology, Hetionet, WikiPathways

Order

MIEF2 covaries with ATG101ProteinHetionet hetionet:covaries:125170-60673Inferred only
MIEF2 covaries with FSTL4ProteinHetionet hetionet:covaries:125170-23105Inferred only
MIEF2 covaries with OPALINProteinHetionet hetionet:covaries:125170-93377Inferred only
PSMF1 interacts with MIEF2ProteinHetionet hetionet:interacts:125170-9491Inferred only
RABAC1 interacts with MIEF2ProteinHetionet hetionet:interacts:10567-125170Inferred only
UBC interacts with MIEF2ProteinHetionet hetionet:interacts:125170-7316Inferred only
UBQLN1 interacts with MIEF2ProteinHetionet hetionet:interacts:125170-29979Inferred only
UBQLN4 interacts with MIEF2ProteinHetionet hetionet:interacts:125170-56893Inferred only
MIEF2 participates in Smith Magenis and Potocki Lupski syndrome copy number variationPathwayWikiPathways WP5381Inferred only
MIEF2 regulates positive regulation of mitochondrial fissionBiological processgene ontology Q96C03|GO:0090141Inferred only
MIEF2 regulates positive regulation of protein targeting to membraneBiological processgene ontology Q96C03|GO:0090314Inferred only
MIEF2 regulates regulation of mitochondrion organizationBiological processgene ontology Q96C03|GO:0010821Inferred only

Other names

5 names

Resolves to: MIEF2

Also called: MID49Mitochondrial dynamics protein of 49 kDaMitochondrial elongation factor 2SMCR7Smith-Magenis syndrome chromosomal region candidate gene 7 protein

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