Proteins/UNIPROT:Q86Y78

LYPD6

ProteinUNIPROT:Q86Y78

Acts as a modulator of nicotinic acetylcholine receptors (nAChRs) function in the brain. Inhibits nicotine-induced Ca(2+) influx through nAChRs. In vitro, specifically inhibits alpha-3:beta-4 and alpha-7 nAChR currents in an allosteric manner. Acts as a positive regulator of Wnt/beta-catenin signaling (By similarity)..

Function from UniProtKB (Q86Y78), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

10 statements

10 statements · 3 reference databases · Subject: LYPD6 · Sources: gene ontology, Hetionet, WikiPathways

Order

LYPD6 covaries with CDK13ProteinHetionet hetionet:covaries:130574-8621Inferred only
LYPD6 covaries with CFAP97ProteinHetionet hetionet:covaries:130574-57587Inferred only
LYPD6 covaries with CXXC5ProteinHetionet hetionet:covaries:130574-51523Inferred only
LYPD6 covaries with DYRK2ProteinHetionet hetionet:covaries:130574-8445Inferred only
LYPD6 covaries with ENHOProteinHetionet hetionet:covaries:130574-375704Inferred only
LYPD6 covaries with SYT5ProteinHetionet hetionet:covaries:130574-6861Inferred only
LYPD6 covaries with VEGFBProteinHetionet hetionet:covaries:130574-7423Inferred only
LYPD6 covaries with ZYXProteinHetionet hetionet:covaries:130574-7791Inferred only
LYPD6 participates in 15q11q13 copy number variationPathwayWikiPathways WP5407Inferred only
LYPD6 regulates positive regulation of canonical Wnt signaling pathwayBiological processgene ontology Q86Y78|GO:0090263Inferred only

Other names

1 name

Resolves to: LYPD6

Also called: Ly6/PLAUR domain-containing protein 6

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