Proteins/UNIPROT:O00453

LST1

ProteinUNIPROT:O00453

Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation..

Function from UniProtKB (O00453), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

4 statements

4 statements · 2 reference databases · Subject: LST1 · Sources: gene ontology, Hetionet

Order

LST1 interacts with CACTINProteinHetionet hetionet:interacts:58509-7940Inferred only
LST1 interacts with G2E3ProteinHetionet hetionet:interacts:55632-7940Inferred only
PRKCB interacts with LST1ProteinHetionet hetionet:interacts:5579-7940Inferred only
LST1 regulates negative regulation of lymphocyte proliferationBiological processgene ontology O00453|GO:0050672Inferred only

Other names

3 names

Resolves to: LST1

Also called: B144Leukocyte-specific transcript 1 proteinProtein B144

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