Proteins/UNIPROT:P83369

LSM11

ProteinUNIPROT:P83369

Component of the U7 snRNP complex that is involved in the histone 3'-end pre-mRNA processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases (By similarity). Binds specifically to the Sm-binding site of U7 snRNA..

Function from UniProtKB (P83369), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

16 statements

16 statements · 3 reference databases · Subject: LSM11 · Sources: gene ontology, Hetionet, Reactome

Order

LSM11 covaries with TPRProteinHetionet hetionet:covaries:134353-7175Inferred only
CLNS1A interacts with LSM11ProteinHetionet hetionet:interacts:1207-134353Inferred only
LSM10 interacts with LSM11ProteinHetionet hetionet:interacts:134353-84967Inferred only
SMN1; SMN2 interacts with LSM11ProteinHetionet hetionet:interacts:134353-6607Inferred only
SMN1; SMN2 interacts with LSM11ProteinHetionet hetionet:interacts:134353-6606Inferred only
SNRPB interacts with LSM11ProteinHetionet hetionet:interacts:134353-6628Inferred only
ZNF473 interacts with LSM11ProteinHetionet hetionet:interacts:134353-25888Inferred only
LSM11 participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
LSM11 participates in Metabolism of RNAPathwayReactome R-HSA-8953854Inferred only
LSM11 participates in Processing of Capped Intronless Pre-mRNAPathwayReactome R-HSA-75067Inferred only
LSM11 participates in RNA Polymerase II TranscriptionPathwayReactome R-HSA-73857Inferred only
LSM11 participates in RNA Polymerase II Transcription TerminationPathwayReactome R-HSA-73856Inferred only

Show the remaining 4

LSM11 participates in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAsPathwayReactome R-HSA-77588Inferred only
LSM11 participates in SLBP independent Processing of Histone Pre-mRNAsPathwayReactome R-HSA-111367Inferred only
LSM11 regulates positive regulation of G1/S transition of mitotic cell cycleBiological processgene ontology P83369|GO:1900087Inferred only
LSM11 regulates regulation of chromatin organizationBiological processgene ontology P83369|GO:1902275Inferred only

Other names

1 name

Resolves to: LSM11

Also called: U7 snRNA-associated Sm-like protein LSm11

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