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Reference

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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:Q9Y2L9

LRCH1

Protein·UNIPROT:Q9Y2L9

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Acts as a negative regulator of GTPase CDC42 by sequestering CDC42-guanine exchange factor DOCK8. Probably by preventing CDC42 activation, negatively regulates CD4(+) T-cell migration..

Function from UniProtKB (Q9Y2L9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

3 statements

3 statements · 2 reference databases · Subject: LRCH1 · Sources: gene ontology, Hetionet

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UBC interacts with LRCH1ProteinHetionet hetionet:interacts:23143-7316Inferred only
LRCH1 regulates negative regulation of GTPase activityBiological processgene ontology Q9Y2L9|GO:0034260Inferred only
LRCH1 regulates negative regulation of T cell migrationBiological processgene ontology Q9Y2L9|GO:2000405Inferred only

Other names

5 names

Resolves to: LRCH1

Also called: Calponin homology domain-containing protein 1CHDC1KIAA1016Neuronal protein 81NP81

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