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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:Q8N6C8

LILRA3

Protein·UNIPROT:Q8N6C8

Open in the graph

Acts as a soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF production by monocytes..

Function from UniProtKB (Q8N6C8), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

6 statements

6 statements · 2 reference databases · Subject: LILRA3 · Sources: Hetionet, Reactome

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EWSR1 interacts with LILRA3ProteinHetionet hetionet:interacts:11026-2130Inferred only
LILRA3 participates in Adaptive Immune SystemPathwayReactome R-HSA-1280218Inferred only
LILRA3 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
LILRA3 participates in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellPathwayReactome R-HSA-198933Inferred only
LILRA3 participates in Innate Immune SystemPathwayReactome R-HSA-168249Inferred only
LILRA3 participates in Neutrophil degranulationPathwayReactome R-HSA-6798695Inferred only

Other names

9 names

Resolves to: LILRA3

Also called: CD antigen CD85eCD85 antigen-like family member EILT-6ILT6Immunoglobulin-like transcript 6Leukocyte immunoglobulin-like receptor 4LIR-4LIR4Monocyte inhibitory receptor HM43/HM31

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