Proteins/UNIPROT:Q8TDN1

KCNG4

ProteinUNIPROT:Q8TDN1

Regulatory subunit of the voltage-gated potassium (Kv) channel which, when coassembled with KCNB1, modulates the kinetics parameters of the heterotetrameric channel namely the time course of activation, deactivation and inactivation and on the voltage-dependence of activation. Potassium channel subunit that does not form functional channels by itself (Probable). Reduces the deactivation rate. Modulates the threshold for activation by shifting by approximately 20 mV in hyperpolarizing direction. Markedly changes the inactivation by shifting the voltage dependence of inactivation by approximately 40 mV in hyperpolarizing direction. Acceleratee activation and enhances the time course of activation..

Function from UniProtKB (Q8TDN1), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

8 statements

8 statements · 3 reference databases · Subject: KCNG4 · Sources: gene ontology, Hetionet, Reactome

Order

KCNG4 covaries with MRPL55ProteinHetionet hetionet:covaries:128308-93107Inferred only
KCNB1 interacts with KCNG4ProteinHetionet hetionet:interacts:3745-93107Inferred only
KCNB2 interacts with KCNG4ProteinHetionet hetionet:interacts:93107-9312Inferred only
KCNG4 participates in Neuronal SystemPathwayReactome R-HSA-112316Inferred only
KCNG4 participates in Potassium ChannelsPathwayReactome R-HSA-1296071Inferred only
KCNG4 participates in Voltage gated Potassium channelsPathwayReactome R-HSA-1296072Inferred only
KCNG4 regulates regulation of potassium ion transmembrane transportBiological processgene ontology Q8TDN1|GO:1901379Inferred only
KCNG4 regulates regulation of potassium ion transportBiological processgene ontology Q8TDN1|GO:0043266Inferred only

Other names

4 names

Resolves to: KCNG4

Also called: KCNG3Potassium voltage-gated channel subfamily G member 4Voltage-gated potassium channel subunit Kv6.3Voltage-gated potassium channel subunit Kv6.4

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