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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:Q13349

ITGAD

Protein·UNIPROT:Q13349

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Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. May play a role in the atherosclerotic process such as clearing lipoproteins from plaques and in phagocytosis of blood-borne pathogens, particulate matter, and senescent erythrocytes from the blood (Probable)..

Function from UniProtKB (Q13349), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

10 statements

10 statements · 3 reference databases · Subject: ITGAD · Sources: Hetionet, Reactome, WikiPathways

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DNAH1 covaries with ITGADProteinHetionet hetionet:covaries:25981-3681Inferred only
ICAM3 interacts with ITGADProteinHetionet hetionet:interacts:3385-3681Inferred only
ITGAD interacts with ITGB2ProteinHetionet hetionet:interacts:3681-3689Inferred only
ITGAD interacts with VCAM1ProteinHetionet hetionet:interacts:3681-7412Inferred only
ITGAD participates in Extracellular matrix organizationPathwayReactome R-HSA-1474244Inferred only
ITGAD participates in Focal adhesion PI3K Akt mTOR signalingPathwayWikiPathways WP3932Inferred only
ITGAD participates in Hippo Merlin signaling dysregulationPathwayWikiPathways WP4541Inferred only
ITGAD participates in Integrin cell surface interactionsPathwayReactome R-HSA-216083Inferred only
ITGAD participates in Integrin mediated cell adhesionPathwayWikiPathways WP185Inferred only
ITGAD participates in Overview of nanoparticle effectsPathwayWikiPathways WP3287Inferred only

Other names

4 names

Resolves to: ITGAD

Also called: ADB2CD antigen CD11dCD11 antigen-like family member DLeukointegrin alpha D

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