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Proteins/UNIPROT:O95998

IL18BP

Protein·UNIPROT:O95998

Open in the graph

Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response..

Function from UniProtKB (O95998), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

11 statements

11 statements · 3 reference databases · Subject: IL18BP · Sources: gene ontology, Hetionet, Reactome

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CEBPB interacts with IL18BPProteinHetionet hetionet:interacts:10068-1051Inferred only
IL18 interacts with IL18BPProteinHetionet hetionet:interacts:10068-3606Inferred only
IL18BP interacts with IL37ProteinHetionet hetionet:interacts:10068-27178Inferred only
IRF1 interacts with IL18BPProteinHetionet hetionet:interacts:10068-3659Inferred only
IL18BP participates in Cytokine Signaling in Immune systemPathwayReactome R-HSA-1280215Inferred only
IL18BP participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
IL18BP participates in Interleukin-1 family signalingPathwayReactome R-HSA-446652Inferred only
IL18BP participates in Interleukin-18 signalingPathwayReactome R-HSA-9012546Inferred only
IL18BP participates in Interleukin-37 signalingPathwayReactome R-HSA-9008059Inferred only
IL18BP participates in Signaling by InterleukinsPathwayReactome R-HSA-449147Inferred only
IL18BP regulates negative regulation of T-helper 1 type immune responseBiological processgene ontology O95998|GO:0002826Inferred only

Other names

2 names

Resolves to: IL18BP

Also called: IL-18BPTadekinig-alfa

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