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Proteins/UNIPROT:Q96FT9

IFT43

Protein·UNIPROT:Q96FT9

Open in the graph

As a component of IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis. Involved in retrograde ciliary transport along microtubules from the ciliary tip to the base..

Function from UniProtKB (Q96FT9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

5 rows

ciliopathy has a germline basis in IFT43DiseaseGenCC HGNC:29669|MONDO:0005308Inferred only
cranioectodermal dysplasia has a germline basis in IFT43DiseaseGenCC HGNC:29669|MONDO:0009032Inferred only
cranioectodermal dysplasia 3 has a germline basis in IFT43DiseaseGenCC HGNC:29669|MONDO:0013573Inferred only
retinitis pigmentosa 81 has a germline basis in IFT43DiseaseGenCC HGNC:29669|MONDO:0036482Inferred only
short-rib thoracic dysplasia 18 with polydactyly has a germline basis in IFT43DiseaseGenCC HGNC:29669|MONDO:0036483Inferred only

Statements

12 statements

12 statements · 3 reference databases · Subject: IFT43 · Sources: Hetionet, Reactome, WikiPathways

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IFT43 covaries with cDNA FLJ59484, highly similar to Nuclear envelope pore membrane protein POM 121ProteinHetionet hetionet:covaries:100101267-112752Inferred only
IFT43 covaries with RPP40ProteinHetionet hetionet:covaries:10799-112752Inferred only
IFT43 covaries with TULP2ProteinHetionet hetionet:covaries:112752-7288Inferred only
IFT43 participates in Assembly of the 9+0 primary ciliumPathwayReactome R-HSA-9975921Inferred only
IFT43 participates in Bardet Biedl syndromePathwayWikiPathways WP5234Inferred only
IFT43 participates in Ciliary landscapePathwayWikiPathways WP4352Inferred only
IFT43 participates in CiliopathiesPathwayWikiPathways WP4803Inferred only
IFT43 participates in Cilium AssemblyPathwayReactome R-HSA-5617833Inferred only
IFT43 participates in Genes related to primary cilium development based on CRISPR PathwayWikiPathways WP4536Inferred only
IFT43 participates in Intraflagellar transportPathwayReactome R-HSA-5620924Inferred only
IFT43 participates in Intraflagellar transport proteins binding to dyneinPathwayWikiPathways WP4532Inferred only
IFT43 participates in Organelle biogenesis and maintenancePathwayReactome R-HSA-1852241Inferred only

Other names

2 names

Resolves to: IFT43

Also called: C14orf179Intraflagellar transport protein 43 homolog

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