Proteins/UNIPROT:P06340

HLA-DOA

ProteinUNIPROT:P06340

Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM.

Function from UniProtKB (P06340), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

13 statements

13 statements · 4 reference databases · Subject: HLA-DOA · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

HLA-DMA interacts with HLA-DOAProteinHetionet hetionet:interacts:3108-3111Inferred only
HLA-DOA interacts with UBCProteinHetionet hetionet:interacts:3111-7316Inferred only
HLA-DOA participates in Adaptive Immune SystemPathwayReactome R-HSA-1280218Inferred only
HLA-DOA participates in Affinity selection of immunoglobulinsPathwayReactome R-HSA-9938027Inferred only
HLA-DOA participates in Allograft rejectionPathwayWikiPathways WP2328Inferred only
HLA-DOA participates in Ebola virus infection in hostPathwayWikiPathways WP4217Inferred only
HLA-DOA participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
HLA-DOA participates in Immunoglobulin maturationPathwayReactome R-HSA-9938026Inferred only
HLA-DOA participates in MHC class II antigen presentationPathwayReactome R-HSA-2132295Inferred only
HLA-DOA participates in Processing of antigen in germinal center B cellsPathwayReactome R-HSA-9979719Inferred only
HLA-DOA regulates negative regulation of antigen processing and presentation of peptide antigen via MHC class IIBiological processgene ontology P06340|GO:0002587Inferred only
HLA-DOA regulates positive regulation of immune responseBiological processgene ontology P06340|GO:0050778Inferred only

Show the remaining 1

HLA-DOA regulates positive regulation of T cell activationBiological processgene ontology P06340|GO:0050870Inferred only

Other names

5 names

Resolves to: HLA-DOA

Also called: HLA-DNAHLA-DZAMHC class II antigen DOAMHC DN-alphaMHC DZ alpha

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