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Proteins/UNIPROT:P69891

HBG1

Protein·UNIPROT:P69891

Open in the graph

Gamma chains make up the fetal hemoglobin F, in combination with alpha chains..

Function from UniProtKB (P69891), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

3 rows

delta-beta-thalassemia has a germline basis in HBG1DiseaseGenCC HGNC:4831|MONDO:0016489Inferred only
hereditary persistence of fetal hemoglobin-beta-thalassemia syndrome has a germline basis in HBG1DiseaseGenCC HGNC:4831|MONDO:0018749Inferred only
hereditary persistence of fetal hemoglobin-sickle cell disease syndrome has a germline basis in HBG1DiseaseGenCC HGNC:4831|MONDO:0016672Inferred only

Statements

8 statements

8 statements · 3 reference databases · Subject: HBG1 · Sources: Hetionet, Reactome, WikiPathways

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APP interacts with HBG1ProteinHetionet hetionet:interacts:3047-351Inferred only
HBG1 interacts with ITGA4ProteinHetionet hetionet:interacts:3047-3676Inferred only
HBG1 interacts with VCAM1ProteinHetionet hetionet:interacts:3047-7412Inferred only
HBG1 participates in Beta globin gene expression regulationPathwayWikiPathways WP5606Inferred only
HBG1 participates in ErythropoiesisPathwayWikiPathways WP5607Inferred only
HBG1 participates in Factors involved in megakaryocyte development and platelet productionPathwayReactome R-HSA-983231Inferred only
HBG1 participates in Hemoglobin switching embryonic fetal and adultPathwayWikiPathways WP5605Inferred only
HBG1 participates in HemostasisPathwayReactome R-HSA-109582Inferred only

Other names

4 names

Resolves to: HBG1

Also called: Gamma-1-globinHb F AgammaHemoglobin gamma-1 chainHemoglobin gamma-A chain

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