Proteins/UNIPROT:Q14832

GRM3

ProteinUNIPROT:Q14832

G protein-coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity..

Function from UniProtKB (Q14832), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

22 statements

22 statements · 4 reference databases · Subject: GRM3 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

GRM3 covaries with HCAR2ProteinHetionet hetionet:covaries:2913-338442Inferred only
GRM3 covaries with NPBProteinHetionet hetionet:covaries:256933-2913Inferred only
GRM3 covaries with ZNF569ProteinHetionet hetionet:covaries:148266-2913Inferred only
CALM1 interacts with GRM3ProteinHetionet hetionet:interacts:2913-808Inferred only
CALM1 interacts with GRM3ProteinHetionet hetionet:interacts:2913-805Inferred only
CALM1 interacts with GRM3ProteinHetionet hetionet:interacts:2913-801Inferred only
GRM3 interacts with GRIP1ProteinHetionet hetionet:interacts:23426-2913Inferred only
GRM3 interacts with PICK1ProteinHetionet hetionet:interacts:2913-9463Inferred only
GRM3 interacts with PPM1AProteinHetionet hetionet:interacts:2913-5494Inferred only
GRM3 interacts with SDCBPProteinHetionet hetionet:interacts:2913-6386Inferred only
GRM3 interacts with TAMALINProteinHetionet hetionet:interacts:160622-2913Inferred only
GRM3 participates in Class C/3 (Metabotropic glutamate/pheromone receptors)PathwayReactome R-HSA-420499Inferred only

Show the remaining 10

GRM3 participates in G alpha (i) signalling eventsPathwayReactome R-HSA-418594Inferred only
GRM3 participates in GABA and glutamate signalling in epileptogenesisPathwayWikiPathways WP5600Inferred only
GRM3 participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
GRM3 participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only
GRM3 participates in GPCRs class C metabotropic glutamate pheromonePathwayWikiPathways WP501Inferred only
GRM3 participates in MelanomaPathwayWikiPathways WP4685Inferred only
GRM3 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
GRM3 participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only
GRM3 regulates negative regulation of adenylate cyclase activityBiological processgene ontology Q14832|GO:0007194Inferred only
GRM3 regulates regulation of synaptic transmission, glutamatergicBiological processgene ontology Q14832|GO:0051966Inferred only

Other names

3 names

Resolves to: GRM3

Also called: GPRC1CMetabotropic glutamate receptor 3MGLUR3

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