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Proteins/UNIPROT:Q8IUY3
Participates in the organization of endoplasmic reticulum-plasma membrane contact sites (EPCS) with pleiotropic functions including STIM1 recruitment and calcium homeostasis. Constitutive tether that co-localize with ESYT2/3 tethers at endoplasmic reticulum-plasma membrane contact sites in a phosphatidylinositol lipid-dependent manner. Pre-marks the subset of phosphtidylinositol 4,5-biphosphate (PI(4,5)P2)-enriched EPCS destined for the store operated calcium entry pathway (SOCE)..
Function from UniProtKB (Q8IUY3), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 statements
3 statements · 2 reference databases · Subject: GRAMD2A · Sources: gene ontology, Hetionet
2 names
Resolves to: GRAMD2A