Proteins/UNIPROT:P51674

GPM6A

ProteinUNIPROT:P51674

Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor..

Function from UniProtKB (P51674), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

6 statements

6 statements · 2 reference databases · Subject: GPM6A · Sources: gene ontology, Hetionet

Order

ZNF331 covaries with GPM6AProteinHetionet hetionet:covaries:2823-55422Inferred only
GPM6A interacts with PAM16ProteinHetionet hetionet:interacts:2823-51025Inferred only
GPM6A interacts with PRKCAProteinHetionet hetionet:interacts:2823-5578Inferred only
GPM6A regulates positive regulation of filopodium assemblyBiological processgene ontology P51674|GO:0051491Inferred only
GPM6A regulates regulation of filopodium assemblyBiological processgene ontology P51674|GO:0051489Inferred only
GPM6A regulates regulation of synapse organizationBiological processgene ontology P51674|GO:0050807Inferred only

Other names

2 names

Resolves to: GPM6A

Also called: M6ANeuronal membrane glycoprotein M6-a

← Every protein Find it in the graph →