Proteins/UNIPROT:Q68DX3

FRMPD2

ProteinUNIPROT:Q68DX3

Functions as a scaffold protein and likely plays a role in N-methyl-D-aspartic acid receptor (NMDAR)-mediated synaptic excitatory transmission (By similarity). May be involved in synapse formation in cone photoreceptor cells (By similarity). May play a role in the regulation of tight junction formation. Binds phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2). May play a role in the regulation of NOD2-mediated NF-kappa-B activation in immune response..

Function from UniProtKB (Q68DX3), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

4 statements

4 statements · 2 reference databases · Subject: FRMPD2 · Sources: Hetionet, WikiPathways

Order

PDE4C covaries with FRMPD2ProteinHetionet hetionet:covaries:143162-5143Inferred only
WDFY4 covaries with FRMPD2ProteinHetionet hetionet:covaries:143162-57705Inferred only
FRMPD2 covaries with ZNF488ProteinHetionet hetionet:covaries:118738-143162Inferred only
FRMPD2 participates in 10q11 21q11 23 copy number variation syndromePathwayWikiPathways WP5352Inferred only

Other names

5 names

Resolves to: FRMPD2

Also called: PDZ domain-containing protein 4PDZ domain-containing protein 5CPDZD5CPDZK4PDZK5C

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