Proteins/UNIPROT:Q4VC44

FLYWCH1

ProteinUNIPROT:Q4VC44

Transcription cofactor. Negatively regulates transcription activation by catenin beta-1 CTNNB1, perhaps acting by competing with TCF4 for CTNNB1 binding. May play a role in DNA-damage response signaling. Binds specifically to DNA sequences at peri-centromeric chromatin loci..

Function from UniProtKB (Q4VC44), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

5 statements

5 statements · 2 reference databases · Subject: FLYWCH1 · Sources: gene ontology, Hetionet

Order

PSME4 covaries with FLYWCH1ProteinHetionet hetionet:covaries:23198-84256Inferred only
ERBB3 interacts with FLYWCH1ProteinHetionet hetionet:interacts:2065-84256Inferred only
SETDB1 interacts with FLYWCH1ProteinHetionet hetionet:interacts:84256-9869Inferred only
UBC interacts with FLYWCH1ProteinHetionet hetionet:interacts:7316-84256Inferred only
FLYWCH1 regulates negative regulation of transcription by RNA polymerase IIBiological processgene ontology Q4VC44|GO:0000122Inferred only

Other names

2 names

Resolves to: FLYWCH1

Also called: FLYWCH-type zinc finger-containing protein 1KIAA1552

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