Proteins/UNIPROT:Q7Z7B0

FILIP1

ProteinUNIPROT:Q7Z7B0

By acting through a filamin-A/F-actin axis, it controls the start of neocortical cell migration from the ventricular zone. May be able to induce the degradation of filamin-A..

Function from UniProtKB (Q7Z7B0), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

neuromuscular disorder, congenital, with dysmorphic facies has a germline basis in FILIP1DiseaseGenCC HGNC:21015|MONDO:0958332Inferred only

Statements

18 statements

18 statements · 3 reference databases · Subject: FILIP1 · Sources: Hetionet, Reactome, WikiPathways

Order

FILIP1 covaries with DUSP15ProteinHetionet hetionet:covaries:128853-27145Inferred only
FILIP1 covaries with FAM171A2ProteinHetionet hetionet:covaries:27145-284069Inferred only
FILIP1 covaries with GPR4ProteinHetionet hetionet:covaries:27145-2828Inferred only
FILIP1 covaries with NPBProteinHetionet hetionet:covaries:256933-27145Inferred only
FILIP1 covaries with OR10A5ProteinHetionet hetionet:covaries:144124-27145Inferred only
OR52E8 covaries with FILIP1ProteinHetionet hetionet:covaries:27145-390079Inferred only
FILIP1 covaries with TUBA8ProteinHetionet hetionet:covaries:27145-51807Inferred only
FILIP1 covaries with ZSWIM4ProteinHetionet hetionet:covaries:27145-65249Inferred only
APP interacts with FILIP1ProteinHetionet hetionet:interacts:27145-351Inferred only
HSF1 interacts with FILIP1ProteinHetionet hetionet:interacts:27145-3297Inferred only
RAD23A interacts with FILIP1ProteinHetionet hetionet:interacts:27145-5886Inferred only
UBC interacts with FILIP1ProteinHetionet hetionet:interacts:27145-7316Inferred only

Show the remaining 6

FILIP1 participates in Integrated breast cancer pathwayPathwayWikiPathways WP1984Inferred only
FILIP1 participates in RHO GTPase cyclePathwayReactome R-HSA-9012999Inferred only
FILIP1 participates in RHOD GTPase cyclePathwayReactome R-HSA-9013405Inferred only
FILIP1 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
FILIP1 participates in Signaling by Rho GTPasesPathwayReactome R-HSA-194315Inferred only
FILIP1 participates in Signaling by Rho GTPases, Miro GTPases and RHOBTB3PathwayReactome R-HSA-9716542Inferred only

Other names

3 names

Resolves to: FILIP1

Also called: Filamin-A-interacting protein 1FILIPKIAA1275

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