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Proteins/UNIPROT:O60258

FGF17

Protein·UNIPROT:O60258

Open in the graph

Plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. Required for normal brain development..

Function from UniProtKB (O60258), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

3 rows

hypogonadotropic hypogonadism has a germline basis in FGF17DiseaseGenCC HGNC:3673|MONDO:0018555Inferred only
hypogonadotropic hypogonadism 20 with or without anosmia has a germline basis in FGF17DiseaseGenCC HGNC:3673|MONDO:0014106Inferred only
Kallmann syndrome has a germline basis in FGF17DiseaseGenCC HGNC:3673|MONDO:0018800Inferred only

Statements

14 statements

14 statements · 3 reference databases · Subject: FGF17 · Sources: gene ontology, Hetionet, WikiPathways

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FGF17 covaries with ALYREFProteinHetionet hetionet:covaries:10189-8822Inferred only
FGF17 covaries with GJB6ProteinHetionet hetionet:covaries:10804-8822Inferred only
FGFR3 interacts with FGF17ProteinHetionet hetionet:interacts:2261-8822Inferred only
FGFR4 interacts with FGF17ProteinHetionet hetionet:interacts:2264-8822Inferred only
FGF17 participates in Breast cancer pathwayPathwayWikiPathways WP4262Inferred only
FGF17 participates in Embryonic stem cell pluripotency pathwaysPathwayWikiPathways WP3931Inferred only
FGF17 participates in Focal adhesion PI3K Akt mTOR signalingPathwayWikiPathways WP3932Inferred only
FGF17 participates in MAPK signalingPathwayWikiPathways WP382Inferred only
FGF17 participates in PI3K Akt signalingPathwayWikiPathways WP4172Inferred only
FGF17 participates in Pleural mesotheliomaPathwayWikiPathways WP5087Inferred only
FGF17 participates in Regulation of actin cytoskeletonPathwayWikiPathways WP51Inferred only
FGF17 regulates positive regulation of cell population proliferationBiological processgene ontology O60258|GO:0008284Inferred only

Show the remaining 2

FGF17 regulates positive regulation of MAPK cascadeBiological processgene ontology O60258|GO:0043410Inferred only
FGF17 regulates regulation of cell migrationBiological processgene ontology O60258|GO:0030334Inferred only

Other names

2 names

Resolves to: FGF17

Also called: FGF-17Fibroblast growth factor 17

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