Proteins/UNIPROT:A0PJY2

FEZF1

ProteinUNIPROT:A0PJY2

Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression is required in OSN to cell-autonomously regulate OSN axon projections. Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. May be required for correct rostral migration of the interneuron progenitors (By similarity)..

Function from UniProtKB (A0PJY2), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

2 rows

hypogonadotropic hypogonadism 22 with or without anosmia has a germline basis in FEZF1DiseaseGenCC HGNC:22788|MONDO:0014461Inferred only
Kallmann syndrome has a germline basis in FEZF1DiseaseGenCC HGNC:22788|MONDO:0018800Inferred only

Statements

7 statements

7 statements · 2 reference databases · Subject: FEZF1 · Sources: gene ontology, Hetionet

Order

PIEZO1 covaries with FEZF1ProteinHetionet hetionet:covaries:389549-9780Inferred only
FEZF1 covaries with TMA7ProteinHetionet hetionet:covaries:389549-51372Inferred only
FEZF1 covaries with TPPPProteinHetionet hetionet:covaries:11076-389549Inferred only
FEZF1 regulates negative regulation of cell population proliferationBiological processgene ontology A0PJY2|GO:0008285Inferred only
FEZF1 regulates positive regulation of DNA-templated transcriptionBiological processgene ontology A0PJY2|GO:0045893Inferred only
FEZF1 regulates regulation of neurogenesisBiological processgene ontology A0PJY2|GO:0050767Inferred only
FEZF1 regulates regulation of transcription by RNA polymerase IIBiological processgene ontology A0PJY2|GO:0006357Inferred only

Other names

4 names

Resolves to: FEZF1

Also called: FEZFez family zinc finger protein 1Zinc finger protein 312BZNF312B

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