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Proteins/UNIPROT:Q9BTP7

FAAP24

Protein·UNIPROT:Q9BTP7

Open in the graph

Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA..

Function from UniProtKB (Q9BTP7), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

12 statements

12 statements · 3 reference databases · Subject: FAAP24 · Sources: Hetionet, Reactome, WikiPathways

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APP interacts with FAAP24ProteinHetionet hetionet:interacts:351-91442Inferred only
FANCM interacts with FAAP24ProteinHetionet hetionet:interacts:57697-91442Inferred only
TRAF6 interacts with FAAP24ProteinHetionet hetionet:interacts:7189-91442Inferred only
FAAP24 participates in Antimicrobial mechanism of IFN-stimulated genesPathwayReactome R-HSA-1169410Inferred only
FAAP24 participates in Cytokine Signaling in Immune systemPathwayReactome R-HSA-1280215Inferred only
FAAP24 participates in DNA RepairPathwayReactome R-HSA-73894Inferred only
FAAP24 participates in Fanconi anemiaPathwayWikiPathways WP5465Inferred only
FAAP24 participates in Fanconi Anemia PathwayPathwayReactome R-HSA-6783310Inferred only
FAAP24 participates in Genes and complexes involved in the DNA repair pathwaysPathwayWikiPathways WP4946Inferred only
FAAP24 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
FAAP24 participates in Interferon SignalingPathwayReactome R-HSA-913531Inferred only
FAAP24 participates in PKR-mediated signalingPathwayReactome R-HSA-9833482Inferred only

Other names

3 names

Resolves to: FAAP24

Also called: C19orf40Fanconi anemia core complex-associated protein 24Fanconi anemia-associated protein of 24 kDa

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