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Proteins/UNIPROT:Q8N693
May coordinately regulate cell cycle progression and transcription during spermatogenesis. Inhibits degradation of polyubiquitinated cyclin A and cyclin B1 and thereby arrests the cell cycle at early M phase. ESXR1-N acts as a transcriptional repressor. Binds to the sequence 5'-TAATGTTATTA-3' which is present within the first intron of the KRAS gene and inhibits its expression. ESXR1-C has the ability to inhibit cyclin turnover..
Function from UniProtKB (Q8N693), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
6 statements
6 statements · 2 reference databases · Subject: ESX1 · Sources: gene ontology, Hetionet
4 names
Resolves to: ESX1