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A reference for what the literature reports. Not medical advice.

Proteins/UNIPROT:Q5T890

ERCC6L2

Protein·UNIPROT:Q5T890

Open in the graph

Promotes double-strand break (DSB) end-joining and facilitates programmed recombination by controlling how DNA ends are joined in a spatially oriented manner during repair (By similarity). Also plays a role in DNA repair by restricting DNA end resection in double strand break (DSB) repair. Facilitates replication of complex DNA regions and regulates the maintenance of chromatin structure..

Function from UniProtKB (Q5T890), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

2 rows

bone marrow failure syndrome has a germline basis in ERCC6L2DiseaseGenCC HGNC:26922|MONDO:0000159Inferred only
pancytopenia-developmental delay syndrome has a germline basis in ERCC6L2DiseaseGenCC HGNC:26922|MONDO:0014317Inferred only

Other names

4 names

Resolves to: ERCC6L2

Also called: C9orf102DNA repair and recombination protein RAD26-likeExcision repair cross-complementation group 6-like 2RAD26L

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