Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Proteins/UNIPROT:Q9NRM1

ENAM

Protein·UNIPROT:Q9NRM1

Open in the graph

Involved in the mineralization and structural organization of enamel. Involved in the extension of enamel during the secretory stage of dental enamel formation..

Function from UniProtKB (Q9NRM1), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

3 rows

amelogenesis imperfecta type 1 has a germline basis in ENAMDiseaseGenCC HGNC:3344|MONDO:0015047Inferred only
amelogenesis imperfecta type 1B has a germline basis in ENAMDiseaseGenCC HGNC:3344|MONDO:0007092Inferred only
amelogenesis imperfecta type 1C has a germline basis in ENAMDiseaseGenCC HGNC:3344|MONDO:0008770Inferred only

Statements

7 statements

7 statements · 3 reference databases · Subject: ENAM · Sources: gene ontology, Hetionet, Reactome

Search this listOrder

ENAM covaries with LEUTXProteinHetionet hetionet:covaries:10117-342900Inferred only
ENAM covaries with MS4A7ProteinHetionet hetionet:covaries:10117-58475Inferred only
ENAM participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
ENAM participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only
ENAM participates in Post-translational protein phosphorylationPathwayReactome R-HSA-8957275Inferred only
ENAM participates in Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)PathwayReactome R-HSA-381426Inferred only
ENAM regulates positive regulation of enamel mineralizationBiological processgene ontology Q9NRM1|GO:0070175Inferred only

Other names

1 name

Resolves to: ENAM

Also called: Enamelin

← Every protein Find it in the graph →