Proteins/UNIPROT:O00423

EML1

ProteinUNIPROT:O00423

Modulates the assembly and organization of the microtubule cytoskeleton, and probably plays a role in regulating the orientation of the mitotic spindle and the orientation of the plane of cell division. Required for normal proliferation of neuronal progenitor cells in the developing brain and for normal brain development. Does not affect neuron migration per se..

Function from UniProtKB (O00423), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

2 rows

band heterotopia of brain has a germline basis in EML1DiseaseGenCC HGNC:3330|MONDO:0010873Inferred only
subcortical band heterotopia has a germline basis in EML1DiseaseGenCC HGNC:3330|MONDO:0020491Inferred only

Statements

7 statements

7 statements · 1 reference database · Subject: EML1 · Sources: Hetionet

Order

CEACAM18 covaries with EML1ProteinHetionet hetionet:covaries:2009-729767Inferred only
PKP4 covaries with EML1ProteinHetionet hetionet:covaries:2009-8502Inferred only
THAP4 covaries with EML1ProteinHetionet hetionet:covaries:2009-51078Inferred only
EML1 interacts with DCUN1D1ProteinHetionet hetionet:interacts:2009-54165Inferred only
EML1 interacts with GRID1ProteinHetionet hetionet:interacts:2009-2894Inferred only
EML1 interacts with GRID2ProteinHetionet hetionet:interacts:2009-2895Inferred only
EML1 interacts with ISG20L2ProteinHetionet hetionet:interacts:2009-81875Inferred only

Other names

5 names

Resolves to: EML1

Also called: EMAP-1EMAP1EMAPLEMAPL1HuEMAP-1

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