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Proteins/UNIPROT:O43854

EDIL3

Protein·UNIPROT:O43854

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Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development.

Function from UniProtKB (O43854), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

9 statements

9 statements · 3 reference databases · Subject: EDIL3 · Sources: gene ontology, Hetionet, Reactome

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OR51A2 covaries with EDIL3ProteinHetionet hetionet:covaries:10085-401667Inferred only
OR52E6 covaries with EDIL3ProteinHetionet hetionet:covaries:10085-390078Inferred only
ITGAV interacts with EDIL3ProteinHetionet hetionet:interacts:10085-3685Inferred only
UBC interacts with EDIL3ProteinHetionet hetionet:interacts:10085-7316Inferred only
EDIL3 participates in Developmental BiologyPathwayReactome R-HSA-1266738Inferred only
EDIL3 participates in MITF-M-dependent gene expressionPathwayReactome R-HSA-9856651Inferred only
EDIL3 participates in MITF-M-regulated melanocyte developmentPathwayReactome R-HSA-9730414Inferred only
EDIL3 participates in Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transitionPathwayReactome R-HSA-9926550Inferred only
EDIL3 regulates positive regulation of cell-substrate adhesionBiological processgene ontology O43854|GO:0010811Inferred only

Other names

3 names

Resolves to: EDIL3

Also called: DEL1Developmentally-regulated endothelial cell locus 1 proteinIntegrin-binding protein DEL1

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