Proteins/UNIPROT:Q9UFH2

DNAH17

ProteinUNIPROT:Q9UFH2

Force generating protein component of the outer dynein arms (ODAs) in the sperm flagellum (By similarity). Produces force towards the minus ends of microtubules (By similarity). Key component of dynein, a family of motor proteins essential for movement along microtubules (By similarity). Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (By similarity). Required for structural and functional integrity of cilia (By similarity). Plays a major role in sperm motility, implicated in sperm flagellar assembly and beating..

Function from UniProtKB (Q9UFH2), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

spermatogenic failure 39 has a germline basis in DNAH17DiseaseGenCC HGNC:2946|MONDO:0032845Inferred only

Statements

3 statements

3 statements · 1 reference database · Subject: DNAH17 · Sources: Hetionet

Order

DNAH17 covaries with DNAH10ProteinHetionet hetionet:covaries:196385-8632Inferred only
DNAH6 covaries with DNAH17ProteinHetionet hetionet:covaries:1768-8632Inferred only
TAAR8 covaries with DNAH17ProteinHetionet hetionet:covaries:83551-8632Inferred only

Other names

7 names

Resolves to: DNAH17

Also called: Axonemal beta dynein heavy chain 17Axonemal dynein heavy chain-like protein 1Ciliary dynein heavy chain 17Ciliary dynein heavy chain-like protein 1DNAHL1DNEL2Dynein axonemal light chain 2

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