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Proteins/UNIPROT:Q8NEG7

DENND6B

Protein·UNIPROT:Q8NEG7

Open in the graph

Guanine nucleotide exchange factor (GEF) for RAB14. Also has some, lesser GEF activity towards RAB35..

Function from UniProtKB (Q8NEG7), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

6 statements

6 statements · 2 reference databases · Subject: DENND6B · Sources: Hetionet, Reactome

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DENND6B covaries with SNURFProteinHetionet hetionet:covaries:414918-8926Inferred only
APP interacts with DENND6BProteinHetionet hetionet:interacts:351-414918Inferred only
DENND6B participates in Membrane TraffickingPathwayReactome R-HSA-199991Inferred only
DENND6B participates in RAB GEFs exchange GTP for GDP on RABsPathwayReactome R-HSA-8876198Inferred only
DENND6B participates in Rab regulation of traffickingPathwayReactome R-HSA-9007101Inferred only
DENND6B participates in Vesicle-mediated transportPathwayReactome R-HSA-5653656Inferred only

Other names

3 names

Resolves to: DENND6B

Also called: DENN domain-containing protein 6BFAM116BProtein DENND6B

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