Proteins/UNIPROT:Q68D51

DENND2C

ProteinUNIPROT:Q68D51

Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form..

Function from UniProtKB (Q68D51), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

5 statements

5 statements · 2 reference databases · Subject: DENND2C · Sources: Hetionet, Reactome

Order

RASGRF1 covaries with DENND2CProteinHetionet hetionet:covaries:163259-5923Inferred only
DENND2C participates in Membrane TraffickingPathwayReactome R-HSA-199991Inferred only
DENND2C participates in RAB GEFs exchange GTP for GDP on RABsPathwayReactome R-HSA-8876198Inferred only
DENND2C participates in Rab regulation of traffickingPathwayReactome R-HSA-9007101Inferred only
DENND2C participates in Vesicle-mediated transportPathwayReactome R-HSA-5653656Inferred only

Other names

1 name

Resolves to: DENND2C

Also called: DENN domain-containing protein 2C

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